A year ago my black 10yr old lab had his second acl surgery. I had him on glucosamine chondroitin & MSM since then. He did improve, but because he is 10, I wanted more quality of life for him. Two weeks ago, I started him on the Glycanaid HA. I see an even bigger improvement. He can jump and stand on both back legs. It may cost more but worth it to see him active. Thanks for a great product!